SYNTHETIC CHEMISTRY
Capabilities include:
‣ Synthesis of Complex molecules from miligrams to grams scale.
‣ Reference standard synthesis.
‣ Small molecules and analogues for lead generation and lead optimisation.
‣ Scaffold synthesis.
‣ Focused libraries upto 200 molecules.
‣ Route scouting.
TECHNOLOGY DEVELOPMENT AND SCALE UP
Capabilities include:
‣ Technology development: A systematic program to study the relevant parameters influencing the yield and quality of the target product.
‣ Ability to synthesize compounds on kilo scale.
‣ Expertise in handling pyrophoric reagents viz n-BuLi, NaH, NaNH2 on a commercial scale.
‣ Experienced in handling of hazardous reagents like NaCN, Br2, Cl2, SO₂, H2S etc. on commercial scale
ANALYTICAL CHEMISTRY
Capabilities include:
‣ Purification of chiral and achiral compounds by preparative chromatography.
‣ Purity by HPLC and GC.
‣ Mass detection by LCMS Analytical method development and validation.
‣ Chiral purity by HPLC.
‣ Moisture content using KF titration.
‣ Wet analysis.
