Our expertise is in handling
- NCE Synthesis
- Library synthesis for HIT identification and Lead identification
- Heterocycles
- Chiral Chemistry – Chiron & Asymmetric synthesis
- Unnatural amino acids
- Small peptides: Solution phase up to Decamers
- Carbohydrates and Aza sugars
- Nucleoside and Nucleotide building blocks
- PROTAC Chemistry
- ADC Linkers
- PEG- Lipids
- Catalyst screening for Buchwald and Suzuki cross coupling reactions
Synthetic Chemistry
- Scaffolds, Building blocks, Reference standards, Intermediates
- Parallel Chemistry, Diversified Library design & synthesis
- Asymmetric synthesis (Stereo-selective, enzymatic & resolution techniques)
- Peptides, Lipid Chemistry, Boronic acids, Oligosaccharides, Polypeptides, Oligo Nucleosides /Nucleotides
- Deuterium labelled compounds, Impurity / Metabolite synthesis
- Synthesis of APIs, stable-labelled intermediates, impurities, API metabolites and glucuronides
Analytical Chemistry
- GLP method development and validation
- Purifications
- Stability studies (ICH)
- Physical characterizations (DSC, TGA, XRD), Impurity profiling & Reference standard characterization
Process R&D and GMP
- Process design, development and optimization
- Process safety studies
- Tech Transfer cGMP and Non-GMP material supplies for Tox, Pre-clinical, Phase 1 / 2
- IND filing support
- 100g to 10 kg , METRIC TONE, and above
Medicinal Chemistry
- Facility available for integrated programs in different therapeutic areas
- Target landscape analysis
- Hit / Lead identification
- SAR/SPR Optimisation
- Lead optimization-DMTA