• IUPAC Name: 2,2′,2”-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid
  • Synonyms: DOTA-​NHS-​ester
  • FW – 501.49
  • CAS No. 170908-81-3
  • Storage temp. Inert atmosphere, Store in freezer, under -20oC
  • Physical Form – off-white solid
  • DOTA-NHS-ester is a useful compound which facilitate the acid-amide coupling in the biological important molecules containing macrocyclic chelator- DOTA ( 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid).
  • The biological application includes in small animals, many different diagnostic and therapeutic applications, such as  MRI contrast agents, PET, SPECT, and CT.
  • It can also be used to label radiotherapeutic agents or imaging probes for the detection of tumors, peptides and antibodies labeling.